Displaced gag diagnosed on MRI

Leiomyoma of the nipple diagnosed by MRI

Leiomyoma of the nipple is a rare, benign, non-epithelial tumor that is thought to arise from smooth muscle fibers in the subareolar tissue of the breast. We report an unusual case of leiomyoma of the nipple in a 32-year-old woman in whom the diagnosis was made by ultrasound-guided core needle biopsy. She came to our hospital complaining of a recently enlarged nipple with discharge and erosion ...

New insights into retroviral Gag–Gag and Gag–membrane interactions

A critical aspect of viral replication is the assembly of virus particles, which are subsequently released as progeny virus. While a great deal of attention has been focused on better understanding this phase of the viral life cycle, many aspects of the molecular details remain poorly understood. This is certainly true for retroviruses, including that of the human immunodeficiency virus type 1 ...

Placenta analysis of prenatally diagnosed patients reveals early GAG storage in mucopolysaccharidoses II and VI.

We analyzed placental tissue in one fetus with MPS II (iduronate sulphatase deficiency) and another with MPS VI (arylsulfatase B deficiency). Both were diagnosed prenatally, but families decided to continue pregnancies and placentas were collected at birth. We were able to demonstrate early storage of GAGs in both diseases by GAG measurement and microscopy analysis. Our results suggest that som...

Anterior cerebral artery dissection diagnosed using high-resolution MRI.

A 51-year-old man was admitted due to weakness (3/5) of the right lower extremity. Brain MRI revealed acute infarcts in the left anterior cerebral artery (ACA) territory (figure, A). Angiographic images demonstrated a stenotic lesion in the left A2 segment (figure, B and C), which high-resolution MRI revealed as a dissection (figure, D and E). Although extensive assessments were conducted, unde...

Infratentorial tumors diagnosed by MRI in pediatric patients